Molecular Networking as a Dereplication Strategy

Jane Y. Yang, Laura M. Sanchez, Christopher M. Rath, +13

Journal of Natural Products

Biomolecular ToolComplex MixturesBiological Mass SpectrometryMolecular BiologyMolecular Computing +15

In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice

Kristen Browder, Pradeep Reddy, Mako Yamamoto, +24

Nature Aging

Developmental BiologyAgingLongevityCell ReprogrammingCellular Senescence +6

A <i>Cutibacterium acnes</i> antibiotic modulates human skin microbiota composition in hair follicles

Jan Claesen, Jennifer Spagnolo, Stephany Flores Ramos, +14

Science Translational Medicine

Development of Antibiotic Activity Profile Screening for the Classification and Discovery of Natural Product Antibiotics

Weng Ruh Wong, Allen G. Oliver, Roger G. Linington

Chemistry & Biology

Natural Product AntibioticsAntimicrobial Drug DiscoveryAntimicrobial SusceptibilityAntibioticsMedicine +8

Examining the Fish Microbiome: Vertebrate-Derived Bacteria as an Environmental Niche for the Discovery of Unique Marine Natural Products

Laura M. Sanchez, Weng Ruh Wong, Romina Riener, +2

PLoS ONE

EngineeringFish IntestinesAquacultureMicrobial EcologyEnvironmental Microbiology +14

MS/MS-based networking and peptidogenomics guided genome mining revealed the stenothricin gene cluster in Streptomyces roseosporus

Wei-Ting Liu, Anne Lamsa, Weng Ruh Wong, +10

The Journal of Antibiotics

Stenothricin Gene ClusterEngineeringOmics DatasetsComputational BiologySynthetic Biology +8

Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis

Anh Tran, Emma E. Watson, Venugopal Pujari, +17

Nature Communications

Bioorganic ChemistryAntimicrobial ChemotherapyNew Tb DrugDrug ResistanceMedicinal Chemistry +16

NP Analyst: An Open Online Platform for Compound Activity Mapping

Jeffrey A. van Santen, Nima Farzaneh, Dennis Y. Liu, +4

ACS Central Science

Hit IdentificationBiological Mass SpectrometryE-scienceData ScienceBioanalysis +21

LOXL4, but not LOXL2, is the critical determinant of pathological collagen cross-linking and fibrosis in the lung

Hsiao‐Yen Ma, Qingling Li, Weng Ruh Wong, +14

Science Advances

An NF-κB-Based High-Throughput Screen Identifies Piericidins as Inhibitors of the Yersinia pseudotuberculosis Type III Secretion System

Miles C. Duncan, Weng Ruh Wong, Allison J. Dupzyk, +3

Antimicrobial Agents and Chemotherapy