Roland Jakob-Røtne

Preclinical Profile of a Potent γ-Secretase Inhibitor Targeting Notch Signaling with <i>In vivo</i> Efficacy and Pharmacodynamic Properties

Leopoldo Luistro, Wei He, Melissa Smith et al. · Cancer Research · 2009 · 188 citations · Full text

Ro4929097 Ic50, Cancer Biology, Tumor Biology +17

Inhibition of the electrostatic interaction between β-amyloid peptide and membranes prevents β-amyloid-induced toxicity

Cornelia Hertel, Evelyne Terzi, Nicole Hauser et al. · Proceedings of the National Academy of Sciences · 1997 · 148 citations

Pharmacological characterization of metabotropic glutamate receptors linked to the inhibition of adenylate cyclase activity in rat striatal slices

Hervé Schaffhauser, Jayne Cartmell, Roland Jakob-Røtne et al. · Neuropharmacology · 1997 · 30 citations

Metabotropic Glutamate Receptors, Neurophysiology, Medicine +9

Design and Synthesis of Novel and Potent Monoamine Oxidase Inhibitors

Quirico Branca, Roland Jakob-Røtne, R. Kettler et al. · CHIMIA International Journal for Chemistry · 1995 · 11 citations · Full text

Combinatorial Chemistry, Organic Chemistry, Pharmacotherapy +16