Antigenic cartography of SARS-CoV-2 reveals that Omicron BA.1 and BA.2 are antigenically distinct

Anna Z. Mykytyn, Melanie Rissmann, Adinda Kok, +18

Science Immunology

ImmunologyPathologyAntigenic CartographyOmicron Ba.1Viral Structural Protein +14

SARS-CoV-2 entry into human airway organoids is serine protease-mediated and facilitated by the multibasic cleavage site

Anna Z. Mykytyn, Tim I. Breugem, Samra Riesebosch, +5

eLife

Protease InhibitorsMultibasic Cleavage SiteSignal TransductionSpike ProteinCoronavirus Entry +13

Susceptibility of rabbits to SARS-CoV-2

Anna Z. Mykytyn, Mart M. Lamers, Nisreen M.A. Okba, +10

Emerging Microbes & Infections

VaccinationRespiratory DiseasesImmunologyVeterinary ScienceFarmed Rabbits +10

Conditionally replicative adenovirus expressing p53 exhibits enhanced oncolytic potency.

Victor W. van Beusechem, Petra B. van den Doel, Jacques Grill, +2

PubMed

Functional P53Viral ReplicationCrad PotencyMedicineApoptosis +11

Interleukin-2-induced, melanoma-specific T cells recognize camel, an unexpected translation product ofLAGE-1

Corlien A. Aarnoudse, Petra B. van den Doel, Bianca Heemskerk, +1

International Journal of Cancer

T-regulatory CellImmune RegulationImmunologyPathologyImmunologic Mechanism +18

Human airway cells prevent SARS-CoV-2 multibasic cleavage site cell culture adaptation

Mart M. Lamers, Anna Z. Mykytyn, Tim I. Breugem, +8

eLife

A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses

Joep Beumer, Maarten H. Geurts, Mart M. Lamers, +13

Nature Communications

Conditionally replicative adenovirus expressing a targeting adapter molecule exhibits enhanced oncolytic potency on CAR-deficient tumors

Victor W. van Beusechem, D C J Mastenbroek, Petra B. van den Doel, +6

Gene Therapy

Adapter Molecule ExhibitsTumor BiologyOncolytic PotencyMedicineImmunology +7

SARS-CoV-2 Omicron efficiently infects human airway, but not alveolar epithelium

Mart M. Lamers, Anna Z. Mykytyn, Tim I. Breugem, +14

Inflammatory Lung DiseaseLung InflammationAdaptive Immune SystemImmunologyImmunodominance +18

Omicron BA.1 and BA.2 are antigenically distinct SARS-CoV-2 variants

Anna Z. Mykytyn, Melanie Rissmann, Adinda Kok, +18

VaccinationVaccine DevelopmentVaccine TargetVaccine SurveillanceImmunology +10