SARS-CoV-2 productively infects human gut enterocytes

Mart M. Lamers, Joep Beumer, Jelte van der Vaart, +18

Science

Divergent SARS-CoV-2 Omicron–reactive T and B cell responses in COVID-19 vaccine recipients

Corine H. GeurtsvanKessel, Daryl Geers, Katharina S. Schmitz, +21

Science Immunology

SARS-CoV-2 Productively Infects Human Gut Enterocytes

Mart M. Lamers, Joep Beumer, Jelte van der Vaart, +18

Viral Target OrganViral EvolutionMucosal ImmunologyDifferentiated EnterocytesViral Pathogenesis +8

An organoid‐derived bronchioalveolar model for SARS‐CoV‐2 infection of human alveolar type II‐like cells

Mart M. Lamers, Jelte van der Vaart, Kèvin Knoops, +17

The EMBO Journal

Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

Philip J. M. Brouwer, Mitch Brinkkemper, Pauline Maisonnasse, +44

Cell

VaccinationMucosal VaccinationCross-protectionVaccine DevelopmentSars-cov-2 Infection +10

Antigenic cartography of SARS-CoV-2 reveals that Omicron BA.1 and BA.2 are antigenically distinct

Anna Z. Mykytyn, Melanie Rissmann, Adinda Kok, +18

Science Immunology

ImmunologyPathologyAntigenic CartographyOmicron Ba.1Viral Structural Protein +14

SARS-CoV-2 entry into human airway organoids is serine protease-mediated and facilitated by the multibasic cleavage site

Anna Z. Mykytyn, Tim I. Breugem, Samra Riesebosch, +5

eLife

Protease InhibitorsMultibasic Cleavage SiteSignal TransductionSpike ProteinCoronavirus Entry +13

Susceptibility of rabbits to SARS-CoV-2

Anna Z. Mykytyn, Mart M. Lamers, Nisreen M.A. Okba, +10

Emerging Microbes & Infections

VaccinationRespiratory DiseasesImmunologyVeterinary ScienceFarmed Rabbits +10

Human airway cells prevent SARS-CoV-2 multibasic cleavage site cell culture adaptation

Mart M. Lamers, Anna Z. Mykytyn, Tim I. Breugem, +8

eLife

A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses

Joep Beumer, Maarten H. Geurts, Mart M. Lamers, +13

Nature Communications