Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

Philip J. M. Brouwer, Mitch Brinkkemper, Pauline Maisonnasse, +44

Cell

VaccinationMucosal VaccinationCross-protectionVaccine DevelopmentSars-cov-2 Infection +10

A public antibody class recognizes an S2 epitope exposed on open conformations of SARS-CoV-2 spike

Mathieu Claireaux, Tom G. Caniels, Marlon de Gast, +30

Nature Communications

COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models

Pauline Maisonnasse, Yoann Aldon, Aurélien Marc, +48

Nature Communications

Antigen- and scaffold-specific antibody responses to protein nanoparticle immunogens

John C. Kraft, Minh N. Pham, Laila Shehata, +24

Cell Reports Medicine

Probing Affinity, Avidity, Anticooperativity, and Competition in Antibody and Receptor Binding to the SARS-CoV-2 Spike by Single Particle Mass Analyses

Victor Yin, Szu‐Hsueh Lai, Tom G. Caniels, +9

ACS Central Science

Virus StructureMass PhotometrySars-cov-2 SpikeVaccine TargetViral Pathogenesis +11

Curcuminoids as EBV Lytic Activators for Adjuvant Treatment in EBV-Positive Carcinomas

Octavia Ramayanti, Mitch Brinkkemper, Sandra A.W.M. Verkuijlen, +3

Cancers

Co-display of diverse spike proteins on nanoparticles broadens sarbecovirus neutralizing antibody responses

Mitch Brinkkemper, Tim S. Veth, Philip J. M. Brouwer, +18

iScience

COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models

Pauline Maisonnasse, Yoann Aldon, Aurélien Marc, +47

Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

Philip J. M. Brouwer, Mitch Brinkkemper, Pauline Maisonnasse, +44

A third SARS-CoV-2 spike vaccination improves neutralization of variants-of-concern

Mitch Brinkkemper, Philip J. M. Brouwer, Pauline Maisonnasse, +14

npj Vaccines

VaccinationVaccine DevelopmentBeta VariantVaccine TargetImmunology +7