Akt-Dependent Metabolic Reprogramming Regulates Tumor Cell Histone Acetylation

Joyce V. Lee, Alessandro Carrer, Supriya Shah, +19

Cell Metabolism

ChromatinChromatin RemodelingMetabolic ReprogrammingMedicineMetabolic Remodeling +3

Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue

David A. Hill, Hee‐Woong Lim, Yong Hoon Kim, +11

Proceedings of the National Academy of Sciences

Prdm16 Is Required for the Maintenance of Brown Adipocyte Identity and Function in Adult Mice

Matthew Harms, Jeff Ishibashi, Wenshan Wang, +6

Cell Metabolism

ObesityMetabolic SyndromeEnergy HomeostasisDevelopmental BiologyMedicine +9

EBF2 Determines and Maintains Brown Adipocyte Identity

Sona Rajakumari, Jun Wu, Jeff Ishibashi, +5

Cell Metabolism

ObesityMolecular PhysiologyPhysiologyMetabolic RegulationMetabolism +4

Deacetylase-Independent Function of HDAC3 in Transcription and Metabolism Requires Nuclear Receptor Corepressor

Zheng Sun, Dan Feng, Bin Fang, +9

Molecular Cell

Transcriptional RegulationDeacetylase-independent FunctionSignal TransductionNatural SciencesMolecular Biology +7

Dynamic Chromatin Remodeling Mediated by Polycomb Proteins Orchestrates Pancreatic Differentiation of Human Embryonic Stem Cells

Ruiyu Xie, Logan J. Everett, Hee‐Woong Lim, +10

Cell stem cell

ChromatinCell LineageDevelopmental BiologyCell SpecializationChromatin Remodeling +8

Ebf2 is a selective marker of brown and beige adipogenic precursor cells

Wenshan Wang, Megan Kissig, Sona Rajakumari, +4

Proceedings of the National Academy of Sciences

Brown Preadipose CellsAdipogenic Precursor CellsInsulin SignalingMetabolic SyndromeTranscriptional Regulation +20

A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate

Wenshan Wang, Jeff Ishibashi, Sophie Trefely, +15

Cell Metabolism

Metabolic SyndromeTranscriptional RegulationSignal TransductionDevelopmental BiologyPrdm16-driven Metabolic Signal +8

Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge

Matthew J. Emmett, Hee‐Woong Lim, Jennifer Jager, +13

Nature

Histone Deacetylase 3ChromatinEnergy HomeostasisEnergy MetabolismHealth Sciences +9

Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo

Seo-Hee You, Hee‐Woong Lim, Zheng Sun, +3

Nature Structural & Molecular Biology

Histone ModificationsChromatinTranscriptional RegulationNuclear Receptor Co-repressorsHistone-deacetylase Activity +9