Concepedia

Christine Gu

CG

11

Publications

326

Citations

10

H-Index

2015

Active since

Affiliations

AbbVie (United States)(Current)

Rice University

National Centre of Scientific Research "Demokritos"

Christine Gu is an author at AbbVie (United States) specializing in medicine, pharmacology, and drug discovery.

Top concepts

MedicinePharmacologyBiochemistryDrug DiscoveryNatural SciencesMedicinal ChemistryDrug AnalysisAntibody EngineeringBiomolecular EngineeringOncology

Publications per year

2015–2022

11

Publications

11

A size exclusion-reversed phase two dimensional-liquid chromatography methodology for stability and small molecule related species in antibody drug conjugates

Yi Li, Christine Gu, Jason Gruenhagen et al. · Journal of Chromatography A · 2015 · 64 citations

Engineering, Medicine, Bioanalysis +12

ABBV-011, A Novel, Calicheamicin-Based Antibody–Drug Conjugate, Targets SEZ6 to Eradicate Small Cell Lung Cancer Tumors

Wolf R. Wiedemeyer, Julia Gavrilyuk, Alexander Schammel et al. · Molecular Cancer Therapeutics · 2022 · 49 citations · Full text

Drug Target, A Novel, Immunology +19

An enzymatic deconjugation method for the analysis of small molecule active drugs on antibody-drug conjugates

Yi Li, Christine Gu, Jason Gruenhagen et al. · mAbs · 2016 · 42 citations · Full text

Papain Deconjugation Approach, Medicinal Chemistry, Bioanalysis +21

Uncialamycin-based antibody–drug conjugates: Unique enediyne ADCs exhibiting bystander killing effect

K. C. Nicolaou, Stephan Rigol, Emmanuel N. Pitsinos et al. · Proceedings of the National Academy of Sciences · 2021 · 41 citations · Full text

Chemical de-conjugation for investigating the stability of small molecule drugs in antibody-drug conjugates

Tao Chen, Dian Su, Jason Gruenhagen et al. · Journal of Pharmaceutical and Biomedical Analysis · 2015 · 27 citations

Medicinal Chemistry, Drug Target, Biochemistry +13

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