Nobuhiro Fujikake

A toxic monomeric conformer of the polyglutamine protein

Yoshitaka Nagai, Takashi Inui, H. Akiko Popiel et al. · Nature Structural & Molecular Biology · 2007 · 334 citations

Protein Chemistry, Protein Assembly, Biochemistry +5

Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal level

Toshihide Takeuchi, Mari Suzuki, Nobuhiro Fujikake et al. · Proceedings of the National Academy of Sciences · 2015 · 210 citations · Full text

Heat Shock Transcription Factor 1-activating Compounds Suppress Polyglutamine-induced Neurodegeneration through Induction of Multiple Molecular Chaperones

Nobuhiro Fujikake, Yoshitaka Nagai, H. Akiko Popiel et al. · Journal of Biological Chemistry · 2008 · 204 citations · Full text

Multiple Molecular Chaperones, Neurodegenerative Diseases, Signal Transduction +15

VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease

Emiko Miura, Takafumi Hasegawa, Masatoshi Konno et al. · Neurobiology of Disease · 2014 · 194 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Synaptic Signaling +7

Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31

Taro Ishiguro, Nozomu Sato, Morio Ueyama et al. · Neuron · 2017 · 133 citations · Full text

Rna Chaperone Tdp-43, Regulatory Role, Natural Sciences +6