Keith Johnson

Molecular basis of myotonic dystrophy: Expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member

J. David Brook, Mila E. McCurrach, H G Harley et al. · Cell · 1992 · 2.8K citations

Signal Transduction, Mendelian Disorder, Genetic Disorder +7

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

René de Waal Malefyt, John B.A.G. Haanen, Hergen Spits et al. · The Journal of Experimental Medicine · 1991 · 1.9K citations · Full text

Adaptive Immune System, T-regulatory Cell, Viral Immunity +20

Cloning of the essential myotonic dystrophy region and mapping of the putative defect

Charalampos Aslanidis, Gert Jansen, Chris T. Amemiya et al. · Nature · 1992 · 499 citations

Rare Diseases, Mendelian Disorder, Medicine +7

Localization of the malignant hyperthermia susceptibility locus to human chromosome 19ql2–13.2

Tommie V. McCarthy, John Healy, J.J.A. Heffron et al. · Nature · 1990 · 372 citations

Hyperthermia, Cytogenetics, Genetic Disorder +10

Trial of Solanezumab in Preclinical Alzheimer’s Disease

Reisa A. Sperling, Michael Donohue, Rema Raman et al. · New England Journal of Medicine · 2023 · 321 citations · Full text