Elevating acetyl-CoA levels reduces aspects of brain aging

António Currais, Ling Huang, Joshua Goldberg, +6

eLife

Alzheimer's DiseaseAgingBiochemistryDrug CandidatesMedicine +13

CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model of Alzheimer's disease

Gamze Ates, Joshua Goldberg, António Currais, +1

Redox Biology

Assaying Cellular Viability Using the Neutral Red Uptake Assay

Gamze Ates, Tamara Vanhaecke, Vera Rogiers, +1

Methods in molecular biology

MedicineIn Vivo SystemBioanalysisCell CultureCellular Viability Using +4

Screening of repeated dose toxicity data present in SCC(NF)P/SCCS safety evaluations of cosmetic ingredients

Mathieu Vinken, Marleen Pauwels, Gamze Ates, +3

Archives of Toxicology

MedicineP/sccs Safety EvaluationsToxicology TestingToxicologyAnalytical Chemistry +6

Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq

Alice Limonciel, Gamze Ates, Giada Carta, +9

Archives of Toxicology

Linking existing in vitro dermal absorption data to physicochemical properties: Contribution to the design of a weight-of-evidence approach for the safety evaluation of cosmetic ingredients with low dermal bioavailability

Gamze Ates, Fabian P. Steinmetz, Tatyana Y. Doktorova, +2

Regulatory Toxicology and Pharmacology

Body CompositionMedicineDrug PurityLow Dermal BioavailabilityToxicology +5

Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes

Umesh Chaudhari, Harshal Nemade, P. Sureshkumar, +6

Archives of Toxicology

<scp>G</scp>enetic deletion of x<scp>CT</scp> attenuates peripheral and central inflammation and mitigates <scp>LPS</scp>‐induced sickness and depressive‐like behavior in mice

Giulia Albertini, Lauren Deneyer, Sigrid Ottestad‐Hansen, +10

Glia

Targeting of intracellular Ca2+ stores as a therapeutic strategy against age-related neurotoxicities

Joshua Goldberg, António Currais, Gamze Ates, +4

npj Aging and Mechanisms of Disease

Retrospective analysis of the mutagenicity/genotoxicity data of the cosmetic ingredients present on the Annexes of the Cosmetic EU legislation (2000–12)

Gamze Ates, Tatyana Y. Doktorova, Marleen Pauwels, +1

Mutagenesis

Low SpecificityRetrospective AnalysisToxicology TestingDermatologyCell Type +14