TNF-alpha-induced microglia activation requires miR-342: impact on NF-kB signaling and neurotoxicity

João Brás, Joana Bravo, Jaime Freitas, +4

Cell Death and Disease

Fibrinogen and magnesium combination biomaterials modulate macrophage phenotype, NF-kB signaling and crosstalk with mesenchymal stem/stromal cells

Mafalda Bessa‐Gonçalves, Andreia Silva, João Brás, +5

Acta Biomaterialia

Tissue EngineeringRegenerative MedicineMagnesium Combination BiomaterialsBiomaterialsEngineering +12

miR-195 inhibits macrophages pro-inflammatory profile and impacts the crosstalk with smooth muscle cells

João Brás, Andreia Silva, George A. Călin, +3

PLoS ONE

ImmunologyImmune RegulationP38 MapkCellular PhysiologyInflammation +18

Stress-induced depressive-like behavior in male rats is associated with microglial activation and inflammation dysregulation in the hippocampus in adulthood

João Brás, Isabelle Guillot de Suduiraut, Olivia Zanoletti, +7

Brain Behavior and Immunity

PsychoneuroimmunologyStress HormonePsychiatryBehavioral NeuroscienceStress +12

miR-99a in bone homeostasis: Regulating osteogenic lineage commitment and osteoclast differentiation

Sara Reis Moura, João Brás, Jaime Freitas, +4

Bone

Developmental BiologyBone Morphogenic ProteinMicrorna DetectionBone HomeostasisGene Expression +5

SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma

Sara Gomes, Bartolomeo Bosco, Joana B. Loureiro, +18

Cancers

Peripheral Biomarkers of Inflammation in Depression: Evidence from Animal Models and Clinical Studies

João Brás, Soraia Pinto, Maria Inês Almeida, +5

Methods in molecular biology

InflammationPsychoneuroimmunologyPsychiatryMood SymptomMedicine +11

Establishment and characterization of human pluripotent stem cells-derived brain organoids to model cerebellar diseases

João Brás, Daniel Henriques, Ricardo Moreira, +7

Scientific Reports

Combining inflammatory miRNA molecules as diagnostic biomarkers for depression: a clinical study

João Brás, Sara Cristina Pinto, Orlando von Doellinger, +5

Frontiers in Psychiatry