Shenghua Wen

PTEN controls tumor-induced angiogenesis

Shenghua Wen, Javor P. Stolarov, Michael P. Myers et al. · Proceedings of the National Academy of Sciences · 2001 · 244 citations · Full text

Medicine, Cancer Biology, Oncology +17

AZD5153: A Novel Bivalent BET Bromodomain Inhibitor Highly Active against Hematologic Malignancies

Garrett W. Rhyasen, Maureen M. Hattersley, Yi Yao et al. · Molecular Cancer Therapeutics · 2016 · 157 citations · Full text

Medicine, Oncology, Pharmacology +17

A Prostate-Specific Membrane Antigen-Targeted Monoclonal Antibody–Chemotherapeutic Conjugate Designed for the Treatment of Prostate Cancer

Michael D. Henry, Shenghua Wen, Matthew D. Silva et al. · Cancer Research · 2004 · 156 citations

Medicine, Oncology, Pharmacology +17

A Human Monoclonal Anti-ANG2 Antibody Leads to Broad Antitumor Activity in Combination with VEGF Inhibitors and Chemotherapy Agents in Preclinical Models

Jeffrey L. Brown, Zhe Cao, Maria Pinzon-Ortiz et al. · Molecular Cancer Therapeutics · 2010 · 153 citations · Full text

Medicine, Oncology, Pharmacology +17

Design and optimisation of dendrimer-conjugated Bcl-2/xL inhibitor, AZD0466, with improved therapeutic index for cancer therapy

Claire Patterson, Srividya B. Balachander, Iain Grant et al. · Communications Biology · 2021 · 95 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14