Alfredo Darmanin-Sheehan

Fundamental Characteristics of the Immunoglobulin VH Repertoire of Chickens in Comparison with Those of Humans, Mice, and Camelids

Leeying Wu, Katarzyna Oficjalska, Matthew Lambert et al. · The Journal of Immunology · 2011 · 85 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Affinity Maturation of a Humanized Rat Antibody for Anti-RAGE Therapy: Comprehensive Mutagenesis Reveals a High Level of Mutational Plasticity Both Inside and Outside the Complementarity-Determining Regions

William J.J. Finlay, Orla Cunningham, Matthew Lambert et al. · Journal of Molecular Biology · 2009 · 64 citations

Pharmacy, Immunology, Antibody Engineering +15

Dissection of the IgNAR V Domain: Molecular Scanning and Orthologue Database Mining Define Novel IgNAR Hallmarks and Affinity Maturation Mechanisms

Brian J. Fennell, Alfredo Darmanin-Sheehan, Simon E. Hufton et al. · Journal of Molecular Biology · 2010 · 41 citations

Life Sciences, Bioinformatics, Molecular Biology +7

CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery

Brian J. Fennell, Barry J. McDonnell, Amy Tam et al. · mAbs · 2013 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmaceutics +17

Advances in biosensors for detection of pathogens in food and water.

Richard O’Kennedy, Paul Leonard, Stephen Hearty et al. · 2005 · 32 citations

Agriculture, Food Science, Microbiology +10