PLGA Based Nanospheres as a Potent Macrophage-Specific Drug Delivery System

Barbora Boltnarova, Jana Kubackova, Josef Škoda, +9

Nanomaterials

Structure–Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase IIβ Interactions

Anna Jirkovská, Galina Karabanovich, Jan Kubeš, +12

Journal of Medicinal Chemistry

Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling

Alejandro Carazo, Ján Dušek, Ondřej Holas, +6

Frontiers in Pharmacology

Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-<i>a</i>]pyridine Structure

Ivana Mejdrová, Ján Dušek, Kryštof Škach, +12

Journal of Medicinal Chemistry

Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain

Josef Škoda, Ján Dušek, Martin Drastík, +7

Cells

Off-target lipid metabolism disruption by the mouse constitutive androstane receptor ligand TCPOBOP in humanized mice

Josef Škoda, Klára Dohnalová, Karel Chalupský, +7

Biochemical Pharmacology