Alaa Alhayek - Concepedia

Author

Alaa Alhayek

Helmholtz Institute for Pharmaceutical Research Saarland ORCID

Also Known As

Alaa Alhayek

Publications

280

Citations

H-Index

Concepts

All Affiliations

Helmholtz Institute for Pharmaceutical Research Saarland Helmholtz Centre for Infection Research Saarland University University of Salzburg University of Groningen

About

Alaa Alhayek is an author at Helmholtz Institute for Pharmaceutical Research Saarland specializing in molecular biology, medicinal chemistry, and medicine.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	2	2	39
2	Natural Sciences	2	2	33
3	Biochemistry	2	2	33
4	Health Sciences	1	1	22
5	Biomolecular Engineering	1	1	22

Alaa Alhayek

Publications

243

Citations

H-Index

Page 1

	Year	Citations
<i>N</i>-Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting <i>Pseudomonas aeruginosa</i> Elastase and <i>Clostridium</i> Collagenases Jelena Konstantinović, Samir Yahiaoui, Alaa Alhayek, Journal of Medicinal Chemistry	2020	34
Hit-optimization using target-directed dynamic combinatorial chemistry: development of inhibitors of the anti-infective target 1-deoxy- <scp>d</scp> -xylulose-5-phosphate synthase Ravindra P. Jumde, Melissa Guardigni, Robin M. Gierse, Chemical Science	2021	33
Substrate‐Inspired Fragment Merging and Growing Affords Efficacious LasB Inhibitors Cansu Kaya, Isabell Walter, Samir Yahiaoui, Angewandte Chemie International Edition Extracellular Virulence FactorsCrystal StructureMolecular BiologyAntimicrobial ChemotherapyPharmaceutical Chemistry	2021	22
Inhibitors of the Elastase LasB for the Treatment of <i>Pseudomonas aeruginosa</i> Lung Infections Jelena Konstantinović, Andreas M. Kany, Alaa Alhayek, ACS Central Science	2023	20
Protein‐Templated Hit Identification through an Ugi Four‐Component Reaction** Federica Mancini, M. Yağız Ünver, Walid A. M. Elgaher, Chemistry - A European Journal	2020	19
Structure-Based Design of α-Substituted Mercaptoacetamides as Inhibitors of the Virulence Factor LasB from <i>Pseudomonas aeruginosa</i> Cansu Kaya, Isabell Walter, Alaa Alhayek, ACS Infectious Diseases	2022	19
First crystal structures of 1-deoxy-d-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis indicate a distinct mechanism of intermediate stabilization Robin M. Gierse, Rick Oerlemans, Eswar R. Reddem, Scientific Reports	2022	19
Phosphonate as a Stable Zinc‐Binding Group for “Pathoblocker” Inhibitors of Clostridial Collagenase H (ColH) Katrin Voos, Esther Schönauer, Alaa Alhayek, ChemMedChem Bioorganic ChemistryStable Zinc‐binding GroupMolecular BiologyAntimicrobial ChemotherapyChemical Biology	2021	17
Identification of a 1-deoxy-D-xylulose-5-phosphate synthase (DXS) mutant with improved crystallographic properties Robin M. Gierse, Eswar R. Reddem, Alaa Alhayek, Biochemical and Biophysical Research Communications Medicinal ChemistryBiosynthesisCellular EnzymologyBiochemistryNatural Sciences	2021	16
Not Every Hit‐Identification Technique Works on 1‐Deoxy‐<scp>d</scp>‐Xylulose 5‐Phosphate Synthase (DXPS): Making the Most of a Virtual Screening Campaign Sandra Johannsen, Robin M. Gierse, Aleksandra Olshanova, ChemMedChem	2023	16

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