Gerda M. Sanvee

The AKT/mTOR signaling pathway plays a key role in statin-induced myotoxicity

Annalisa Bonifacio, Gerda M. Sanvee, Jamal Bouitbir et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2015 · 92 citations

Inflammation, Cytokine, Reductive Stress +10

Mechanisms of insulin resistance by simvastatin in C2C12 myotubes and in mouse skeletal muscle

Gerda M. Sanvee, Miljenko V. Panajatovic, Jamal Bouitbir et al. · Biochemical Pharmacology · 2019 · 48 citations

Insulin Resistance, Metabolic Syndrome, Insulin Signaling +14

IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes

Annalisa Bonifacio, Gerda M. Sanvee, Karin Brecht et al. · Archives of Toxicology · 2016 · 32 citations

Inflammation, Endothelial Dysfunction, Cell Death +4

mTORC2 is an important target for simvastatin-associated toxicity in C2C12 cells and mouse skeletal muscle – Roles of Rap1 geranylgeranylation and mitochondrial dysfunction

Gerda M. Sanvee, Leonie Hitzfeld, Jamal Bouitbir et al. · Biochemical Pharmacology · 2021 · 32 citations · Full text

Mitochondrial Dysfunction, Mtorc1 Inhibitor Rapamycin, Cell Death +20

Molecular Toxicological Mechanisms of Synthetic Cathinones on C2C12 Myoblasts

Xun Zhou, Dino Luethi, Gerda M. Sanvee et al. · International Journal of Molecular Sciences · 2019 · 24 citations · Full text

Molecular Pharmacology, Biosynthesis, Biochemistry +11