Concepedia

Author

Eleanor Howgate

Simcyp (United Kingdom)

Also Known As

E. M. Howgate, Eleanor Howgate, Eleanor M Howgate, Eleanor M. Howgate

13

Publications

526

Citations

8

H-Index

25

Concepts

All Affiliations

Simcyp (United Kingdom)University of SheffieldRoyal Hallamshire Hospital
EH

About

Eleanor Howgate is an author at Simcyp (United Kingdom) specializing in medicine, pharmacokinetics, and pharmacokinetic modeling.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

3

3

161

2

Pharmacology

3

3

161

3

Biostatistics

2

2

143

4

Health Sciences

1

1

54

5

Metabolism

1

1

54

Eleanor Howgate

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7

Publications

499

Citations

7

H-Index

YearCitations

Prediction of<i>in vivo</i>drug clearance from<i>in vitro</i>data. I: Impact of inter-individual variability

Eleanor Howgate, Karen Rowland Yeo, N. J. Proctor,

Xenobiotica

2006

219

Prediction of<i>in vivo</i>drug clearance from<i>in vitro</i>data. II: Potential inter-ethnic differences

Shinichi Inoue, Eleanor Howgate, K Rowland‐Yeo,

Xenobiotica

2006

89

Prediction of metabolic drug clearance in humans:<b><i>In vitro–in vivo</i></b>extrapolation<b><i>vs</i></b>allometric scaling

Mohammad Bagher Shiran, N. J. Proctor, Eleanor Howgate,

Xenobiotica

2006

88

Sources of interindividual variability in IVIVE of clearance: an investigation into the prediction of benzodiazepine clearance using a mechanistic population-based pharmacokinetic model

H Cubitt, Karen Rowland Yeo, Eleanor Howgate,

Xenobiotica

2011

54

Development and application of a PBPK modeling strategy to support antimalarial drug development

Nada Abla, Eleanor Howgate, Karen Rowland Yeo,

CPT Pharmacometrics & Systems Pharmacology

2023

18

Population pharmacokinetics of the MEK inhibitor selumetinib and its active N‐desmethyl metabolite: data from 10 phase I trials

Parul Patel, Eleanor Howgate, Paul Martin,

British Journal of Clinical Pharmacology

2017

17

Use of Developmental Midazolam and 1-Hydroxymidazolam Data with Pediatric Physiologically Based Modeling to Assess Cytochrome P450 3A4 and Uridine Diphosphate Glucuronosyl Transferase 2B4 Ontogeny In Vivo

Trevor N. Johnson, Eleanor Howgate, Saskia N. de Wildt,

Drug Metabolism and Disposition

2023

14

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