Cell-permeable Peptide Antioxidants Targeted to Inner Mitochondrial Membrane inhibit Mitochondrial Swelling, Oxidative Cell Death, and Reperfusion Injury

Kesheng Zhao, Guomin Zhao, Dunli Wu, +4

Journal of Biological Chemistry

The Mitochondrial-Targeted Compound SS-31 Re-Energizes Ischemic Mitochondria by Interacting with Cardiolipin

Alexander Birk, Shaoyi Liu, Yi Soong, +6

Journal of the American Society of Nephrology

Signal TransductionOxysterolBiochemistryMitochondrial FunctionRenal Ischemia +13

Mitochondria-Targeted Peptide Accelerates ATP Recovery and Reduces Ischemic Kidney Injury

Hazel H. Szeto, Shaoyi Liu, Yi Soong, +7

Journal of the American Society of Nephrology

Mitochondrial Permeability TransitionCell DeathReactive Oxygen SpeciesRedox BiologyOxidative Stress +15

Protection of mitochondria prevents high-fat diet–induced glomerulopathy and proximal tubular injury

Hazel H. Szeto, Shaoyi Liu, Yi Soong, +3

Kidney International

Mitochondria Protection after Acute Ischemia Prevents Prolonged Upregulation of IL-1β and IL-18 and Arrests CKD

Hazel H. Szeto, Shaoyi Liu, Yi Soong, +5

Journal of the American Society of Nephrology

Potent mitochondria-targeted peptides reduce myocardial infarction in rats

Janghyun Cho, Kyung-Heon Won, Dunli Wu, +4

Coronary Artery Disease

Novel cardiolipin therapeutic protects endothelial mitochondria during renal ischemia and mitigates microvascular rarefaction, inflammation, and fibrosis

Shaoyi Liu, Yi Soong, Surya V. Seshan, +1

American Journal of Physiology-Renal Physiology

In vivo pharmacokinetics of selective mu-opioid peptide agonists.

Hazel H. Szeto, Jerry L. Lovelace, Genevieve Fridland, +5

PubMed

Molecular PharmacologyGreater SelectivityBiochemistryMedicineVivo Pharmacokinetics +11

Profound Spinal Tolerance after Repeated Exposure to a Highly Selective μ-Opioid Peptide Agonist: Role of δ-Opioid Receptors

Guomin Zhao, Dunli Wu, Yi Soong, +4

Journal of Pharmacology and Experimental Therapeutics

Disruption of cytochrome c heme coordination is responsible for mitochondrial injury during ischemia

Alexander Birk, Wesley Chao, Shaoyi Liu, +2

Biochimica et Biophysica Acta (BBA) - Bioenergetics

BiochemistryMitochondrial FunctionNatural SciencesHeme HomeostasisPhysiology +7