Hadley E. Sheppard

Small-molecule targeting of brachyury transcription factor addiction in chordoma

Tanaz Sharifnia, Mathias J. Wawer, Ting Chen et al. · Nature Medicine · 2019 · 160 citations

Transcriptional Regulation, Signaling Pathway, Natural Sciences +4

Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity

Hadley E. Sheppard, Alessandra Dall’Agnese, Woojun D. Park et al. · Cell Reports Medicine · 2021 · 38 citations · Full text

IRF2 is a master regulator of human keratinocyte stem cell fate

Nicolas Mercado, Gabi Schutzius, Christian Kolter et al. · Nature Communications · 2019 · 37 citations · Full text

Democratizing clinical-genomic data: How federated platforms can promote benefits sharing in genomics

Maria L. Alvarellos, Hadley E. Sheppard, Ingrid Knarston et al. · Frontiers in Genetics · 2023 · 32 citations · Full text

Family Medicine, Engineering, Sequencing Costs +22

Computational Drug Repositioning Identifies Potentially Active Therapies for Chordoma

Jeffrey I. Traylor, Hadley E. Sheppard, Visweswaran Ravikumar et al. · Neurosurgery · 2020 · 16 citations · Full text