Roger Léger

Identification and Characterization of Inhibitors of Multidrug Resistance Efflux Pumps in <i>Pseudomonas aeruginosa</i> : Novel Agents for Combination Therapy

Olga Lomovskaya, Mark S. Warren, Angela Lee et al. · Antimicrobial Agents and Chemotherapy · 2001 · 889 citations · Full text

Life Sciences, Infectious Diseases, Pharmacology +17

Inhibitors of Efflux Pumps in <i>Pseudomonas </i><i>a</i><i>eruginosa</i> Potentiate the Activity of the Fluoroquinolone Antibacterial Levofloxacin

Thomas E. Renau, Roger Léger, Eric M. Flamme et al. · Journal of Medicinal Chemistry · 1999 · 256 citations

Medicine, Pharmacology, Antimicrobial Pharmacology +15

Conformationally-restricted analogues of efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa

Thomas E. Renau, Roger Léger, L. K. FILONOVA et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 97 citations

Life Sciences, Medicinal Chemistry, Pharmacology +16

MexAB-OprM-Specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 1: Discovery and early strategies for lead optimization

Kiyoshi Nakayama, Yohei Ishida, Masami Ohtsuka et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 82 citations

Pharmacy, Microbiology, Pharmacology +17

Peptidomimetics of Efflux Pump Inhibitors Potentiate the Activity of Levofloxacin in Pseudomonas aeruginosa

Thomas E. Renau, Roger Léger, Rose Yen et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 80 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14