Strong Association of De Novo Copy Number Mutations with Autism

Jonathan Sebat, B. Lakshmi, Dheeraj Malhotra, +29

Science

PsychiatryAutism Spectrum DisordersSyndromic AutismGeneticsGenetic Disorder +11

The contribution of de novo coding mutations to autism spectrum disorder

Ivan Iossifov, Brian J. O’Roak, Stephan Sanders, +44

Nature

Neurodevelopmental DisordersSpectrum DisorderSyndromic AutismGenetic DisorderGenetics +6

De Novo Gene Disruptions in Children on the Autistic Spectrum

Ivan Iossifov, Michael Ronemus, Dan Levy, +32

Neuron

Developmental BiologySyndromic AutismGenetic DisorderGeneticsAutism +6

Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

Dan Levy, Michael Ronemus, Boris Yamrom, +14

Neuron

Neurodevelopmental DisordersRare De NovoPsychiatrySyndromic AutismGenetic Disorder +8

Increased Frequency of De Novo Copy Number Variants in Congenital Heart Disease by Integrative Analysis of Single Nucleotide Polymorphism Array and Exome Sequence Data

Joseph Glessner, Alexander G. Bick, Kaoru Ito, +27

Circulation Research

Low load for disruptive mutations in autism genes and their biased transmission

Ivan Iossifov, Dan Levy, Jeremy Allen, +5

Proceedings of the National Academy of Sciences

The contribution of de novo and rare inherited copy number changes to congenital heart disease in an unselected sample of children with conotruncal defects or hypoplastic left heart disease

Dorothy Warburton, Michael Ronemus, Jennie Kline, +14

Human Genetics

Heart FailureCardiovascular DiseasePediatric Heart DiseaseGeneticsPediatrics +8

Novel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA)

Vladimir Grubor, A. Krasnitz, Jennifer Troge, +17

Blood

Rates of contributory de novo mutation in high and low-risk autism families

Seungtai Yoon, Adriana Muñoz, Boris Yamrom, +14

Communications Biology

Robust Extraction of Metaphor from Novel Data

Tomek Strzalkowski, George Aaron Broadwell, Sarah Taylor, +8

EngineeringLexical SemanticsSemanticsSystem PrototypeCorpus Linguistics +16