Stephen P. Jung

Inhibiting expression of specific genes in mammalian cells with 5′ end-mutated U1 small nuclear RNAs targeted to terminal exons of pre-mRNA

Puri Fortes, Yolanda Cuevas, Fei Guan et al. · Proceedings of the National Academy of Sciences · 2003 · 78 citations · Full text

Engineering, Genetics, Molecular Biology +19

Requirements for gene silencing mediated by U1 snRNA binding to a target sequence

Xabi Abad, María Vera, Stephen P. Jung et al. · Nucleic Acids Research · 2008 · 53 citations · Full text

Structure–Activity Relationship (SAR) Optimization of 6-(Indol-2-yl)pyridine-3-sulfonamides: Identification of Potent, Selective, and Orally Bioavailable Small Molecules Targeting Hepatitis C (HCV) NS4B

Nanjing Zhang, Xiaoyan Zhang, Jin Zhu et al. · Journal of Medicinal Chemistry · 2013 · 43 citations · Full text

Structure–activity Relationship, Pharmaceutical Science, Immunology +18

Identification of PTC725, an Orally Bioavailable Small Molecule That Selectively Targets the Hepatitis C Virus NS4B Protein

Zhengxian Gu, Jason D. Graci, Frederick Lahser et al. · Antimicrobial Agents and Chemotherapy · 2013 · 19 citations · Full text

Immunology, Molecular Biology, Hcv 1B +16

Discovery of 2-(4-sulfonamidophenyl)-indole 3-carboxamides as potent and selective inhibitors with broad hepatitis C virus genotype activity targeting HCV NS4B

Nanjing Zhang, Anthony Turpoff, Xiaoyan Zhang et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 16 citations

Biochemistry, Viral Hepatitis, Medicine +8