Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation

Nathan W. Bartlett, Ross P. Walton, Michael R. Edwards, +25

Nature Medicine

AllergyInflammatory Lung DiseaseLung InflammationRespiratory DiseasesImmunology +8

A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses

Tiong Kit Tan, Pramila Rijal, Rolle Rahikainen, +51

Nature Communications

Picornaviruses

Tobias J. Tuthill, Elisabetta Groppelli, James M. Hogle, +1

Current topics in microbiology and immunology

Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

Simon P. Graham, Rebecca McLean, Alexandra J. Spencer, +39

npj Vaccines

Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus

Aurélie Mousnier, Andrew Bell, Dawid Swieboda, +16

Nature Chemistry

Virus StructureViral ReplicationSynthetic VirologyAntiviral Drug DevelopmentMolecular Biology +7

Characterization of Early Steps in the Poliovirus Infection Process: Receptor-Decorated Liposomes Induce Conversion of the Virus to Membrane-Anchored Entry-Intermediate Particles

Tobias J. Tuthill, Doryen Bubeck, David J. Rowlands, +1

Journal of Virology

Cell-based Vaccine ProductionVirus StructureViral ReplicationPoliovirus Infection ProcessMolecular Virology +12

Capsid Protein VP4 of Human Rhinovirus Induces Membrane Permeability by the Formation of a Size-Selective Multimeric Pore

Anusha Panjwani, Mike Strauss, Sarah Gold, +7

PLoS Pathogens

Virus StructureViral ReplicationCapsid Protein Vp4Non-enveloped VirusMolecular Virology +11

A plate-based high-throughput assay for virus stability and vaccine formulation

Thomas S. Walter, Jingshan Ren, Tobias J. Tuthill, +3

Journal of Virological Methods

Virus StabilityViral DiagnosticsImmunologyVirus Particle StabilityVaccine Target +15

Inhibition of hepatitis C virus p7 membrane channels in a liposome-based assay system

Corine StGelais, Tobias J. Tuthill, David Clarke, +3

Antiviral Research

Liposome-based Assay SystemBiochemistryViral HepatitisImmunologyAntiviral Drug Development +6

Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies

Kirby N. Swatek, Martina Aumayr, Jonathan N. Pruneda, +9

Proceedings of the National Academy of Sciences