Xianxin Hua

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

Xiaodong Wang, Ryuichiro Sato, Michael S. Brown et al. · Cell · 1994 · 999 citations

Signal Transduction, Biochemistry, Natural Sciences +8

SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene

Chieko Yokoyama, Xiaodong Wang, Michael R. Briggs et al. · Cell · 1993 · 948 citations

Proteinlipid Interaction, Protein Function, Biochemistry +5

SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element.

Xianxin Hua, Chieko Yokoyama, Jiang Wu et al. · Proceedings of the National Academy of Sciences · 1993 · 610 citations · Full text

Molecular Regulation, Genetics, Molecular Biology +18

Sterol-Regulated Release of SREBP-2 from Cell Membranes Requires Two Sequential Cleavages, One Within a Transmembrane Segment

Juro Sakai, Elizabeth A. Duncan, Robert B. Rawson et al. · Cell · 1996 · 523 citations · Full text

Proteinlipid Interaction, Signal Transduction, Biochemistry +14

Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth

Jiajun Zhu, Morgan A. Sammons, Greg Donahue et al. · Nature · 2015 · 482 citations · Full text

Cancer Research, Chromatin, Chromatin Remodeling +10