EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step

Satoshi Ninagawa, Tetsuya Okada, Yoshiki Sumitomo, +8

The Journal of Cell Biology

UPR transducer BBF2H7 allows export of type II collagen in a cargo- and developmental stage–specific manner

Tokiro Ishikawa, Takuya Toyama, Yuki Nakamura, +11

The Journal of Cell Biology

ATF6α/β-mediated adjustment of ER chaperone levels is essential for development of the notochord in medaka fish

Tokiro Ishikawa, Tetsuya Okada, Tomoko Ishikawa‐Fujiwara, +12

Molecular Biology of the Cell

Comparative EndocrinologyMolecular RegulationMolecular GeneticsEr StressTranscriptional Regulation +21

EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD

Ginto George, Satoshi Ninagawa, Hirokazu Yagi, +9

eLife

Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is not required for growth and development of medaka fish

Tokiro Ishikawa, Makoto Kashima, Atsushi J. Nagano, +4

eLife

GeneticsMolecular GeneticsTranscriptional RegulationSignaling PathwayXbp1 Mrna Splicing +16

Vertebrate Unfolded Protein Response: Mammalian Signaling Pathways Are Conserved in Medaka Fish

Tokiro Ishikawa, Yoshihito Taniguchi, Tetsuya Okada, +2

Cell Structure and Function

Molecular RegulationEr StressProtein ResponseCellular PhysiologySignaling Pathway +17

Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway

Satoshi Ninagawa, Tetsuya Okada, Yoshiki Sumitomo, +9

The Journal of Cell Biology

Antipsychotic olanzapine-induced misfolding of proinsulin in the endoplasmic reticulum accounts for atypical development of diabetes

Satoshi Ninagawa, Seiichiro Tada, Masaki Okumura, +13

eLife

Bystander Effect between Zebrafish Embryos in Vivo Induced by High-Dose X-rays

V. W. Y. Choi, C. Y. P. Ng, Alisa Kobayashi, +5

Environmental Science & Technology

OocyteFertilityRadiation EffectNaive EmbryosRadiation Exposure +16

Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD

Ginto George, Satoshi Ninagawa, Hirokazu Yagi, +12

eLife