Improving polygenic prediction in ancestrally diverse populations

Yunfeng Ruan, Yen‐Chen Anne Feng, Chia‐Yen Chen, +3

Nature Genetics

Genetic DiversityMolecular EcologyMedicineGeneticsEvolutionary Biology +6

A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease

Aniruddh P. Patel, Minxian Wang, Yunfeng Ruan, +17

Nature Medicine

Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization

Hao Li, Yunfeng Ruan, Kuan Zhang, +10

Cell Death and Differentiation

Mitochondrial FunctionMitochondrial DynamicMic60/mitofilin Determines MicosNatural SciencesMitochondrial Dynamics +7

PRSet: Pathway-based polygenic risk score analyses and software

Shing Wan Choi, Judit García‐González, Yunfeng Ruan, +5

PLoS Genetics

Improving Polygenic Prediction in Ancestrally Diverse Populations

Yunfeng Ruan, Yen‐Chen Anne Feng, Chia‐Yen Chen, +2

GeneticsPolygenic RiskGenetic EpidemiologyGenome-wide Association StudiesGenome-wide Association Study +21

Genetic modification of inflammation- and clonal hematopoiesis–associated cardiovascular risk

Zhi Yu, Trevor P. Fidler, Yunfeng Ruan, +25

Journal of Clinical Investigation

Integrative polygenic risk score improves the prediction accuracy of complex traits and diseases

Buu Truong, Leland E. Hull, Yunfeng Ruan, +8

Cell Genomics

Loss of Yme1L perturbates mitochondrial dynamics

Yunfeng Ruan, Hao Li, Kuan Zhang, +2

Cell Death and Disease

MitophagyAaa ProteaseMitochondrial FunctionMitochondrial DynamicMedicine +13

Measured Blood Pressure, Genetically Predicted Blood Pressure, and Cardiovascular Disease Risk in the UK Biobank

So Mi Jemma Cho, Satoshi Koyama, Yunfeng Ruan, +7

JAMA Cardiology

Comparative genome analysis of Prevotella intermedia strain isolated from infected root canal reveals features related to pathogenicity and adaptation

Yunfeng Ruan, Lu Shen, Yan Zou, +8

BMC Genomics