Conserved pan-cancer microenvironment subtypes predict response to immunotherapy

Alexander Bagaev, Nikita Kotlov, Krystle Nomie, +10

Cancer Cell

Pan-cancer Microenvironment SubtypesCancer ImmunosurveillanceImmunologyImmune Checkpoint InhibitorImmunotherapy +4

Clinical and Biological Subtypes of B-cell Lymphoma Revealed by Microenvironmental Signatures

Nikita Kotlov, Alexander Bagaev, María V. Revuelta, +18

Cancer Discovery

Laminin assembles into separate basement membrane and fibrillar matrices in Schwann cells

Maria Tsiper, Peter D. Yurchenco

Journal of Cell Science

Endogenous presenilin 1 redistributes to the surface of lamellipodia upon adhesion of Jurkat cells to a collagen matrix

A. L. Schwarzman, Nandita Singh, Maria Tsiper, +6

Proceedings of the National Academy of Sciences

Amyloidogenic and anti-amyloidogenic properties of recombinant transthyretin variants

A. L. Schwarzman, Maria Tsiper, Henning Wente, +4

Amyloid

Recombinant Transthyretin VariantsBeta Amyloid FormationAlzheimer's DiseaseBiochemistryNatural Sciences +7

Differential Mitochondrial Toxicity Screening and Multi-Parametric Data Analysis

Maria Tsiper, Jennifer Sturgis, Larisa Avramova, +9

PLoS ONE

Mitochondrial DysfunctionMetabolomic ProfilingMulti-parametric Data AnalysisOxidative StressBioanalysis +16

Multiregional single-cell proteogenomic analysis of ccRCC reveals cytokine drivers of intratumor spatial heterogeneity

Natalia Miheecheva, Ekaterina Postovalova, Yang Lyu, +17

Cell Reports

Phenotypic Profiling of Raf Inhibitors and Mitochondrial Toxicity in 3D Tissue Using Biodynamic Imaging

Ran An, Dan Merrill, Larisa Avramova, +5

SLAS DISCOVERY

EngineeringOncologic ImagingRaf Kinase InhibitorsCell CultureRaf Inhibitors +20

The Role of Alzheimer's Disease-Related Presenilin 1 in Intercellular Adhesion

Nandita Singh, Yelena Talalayeva, Maria Tsiper, +9

Experimental Cell Research

Alzheimer's DiseaseIntercellular AdhesionCell AdhesionDementiaDegenerative Pathology +8

Single-cell Spatial Proteomic Revelations on the Multiparametric MRI Heterogeneity of Clinically Significant Prostate Cancer

Russell K. Pachynski, Eric H. Kim, Natalia Miheecheva, +18

Clinical Cancer Research