Spatially resolved proteomic mapping in living cells with the engineered peroxidase APEX2

Victoria Hung, Namrata D. Udeshi, Stephanie S Lam, +5

Nature Protocols

Proteomic TechnologyBiochemistryEngineered Peroxidase Apex2Natural SciencesMedicine +10

A Coiled-Coil Enabled Split-Luciferase Three-Hybrid System: Applied Toward Profiling Inhibitors of Protein Kinases

Benjamin W. Jester, Kurt J. Cox, Alicia Gaj, +3

Journal of the American Chemical Society

Drug TargetProtein AssemblyMolecular BiologyProtein FoldingReceptor Tyrosine Kinase +15

Engineering designer beta cells with a CRISPR-Cas9 conjugation platform

Donghyun Lim, Vedagopuram Sreekanth, Kurt J. Cox, +4

Nature Communications

Small-Molecule Control of Super-Mendelian Inheritance in Gene Drives

Víctor López Del Amo, Brittany S. Leger, Kurt J. Cox, +6

Cell Reports

EngineeringGeneticsGenomic MechanismMolecular GeneticsModified Spcas9 +16

A Singular System with Precise Dosing and Spatiotemporal Control of CRISPR‐Cas9

Debasish Manna, Basudeb Maji, Soumyashree A. Gangopadhyay, +5

Angewandte Chemie International Edition

EngineeringGeneticsMolecular BiologyBiological ComputingOptogenetics +18

Testing the Promiscuity of Commercial Kinase Inhibitors Against the AGC Kinase Group Using a Split-luciferase Screen

Benjamin W. Jester, Alicia Gaj, Carolyn D. Shomin, +2

Journal of Medicinal Chemistry

Drug TargetEngineeringTumor BiologyReceptor Tyrosine KinaseBioanalysis +17

A universal method for sensitive and cell-free detection of CRISPR-associated nucleases

Kurt J. Cox, Hari K. K. Subramanian, Christian Cuba Samaniego, +2

Chemical Science

A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules

Donghyun Lim, Qingxuan Zhou, Kurt J. Cox, +19

Nature Cell Biology

EngineeringBiomolecular ToolMedicineMolecular BiologyGenetic Engineering +10

Selection of cyclic-peptide inhibitors targeting Aurora kinase A: Problems and solutions

Carolyn D. Shomin, Elizabeth Restituyo, Kurt J. Cox, +1

Bioorganic & Medicinal Chemistry

Medicinal ChemistrySignal TransductionMedicineReceptor Tyrosine KinasePeptide Therapeutic +9