Marc N. Offman

A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease

Alexander Zimprich, Anna Benet‐Pagès, Walter Struhal et al. · The American Journal of Human Genetics · 2011 · 876 citations · Full text

Late-onset Parkinson Disease, Retromer Complex, Neurodegenerative Diseases +8

Rational engineering of L-asparaginase reveals importance of dual activity for cancer cell toxicity

Marc N. Offman, Marcin Król, Naina Patel et al. · Blood · 2010 · 162 citations · Full text

A dyad of lymphoblastic lysosomal cysteine proteases degrades the antileukemic drug l-asparaginase

Naina Patel, Shekhar Krishnan, Marc N. Offman et al. · Journal of Clinical Investigation · 2009 · 117 citations · Full text

Pathology, Molecular Biology, Chemical Biology +18

Molecular Basis of Reduced Glucosylceramidase Activity in the Most Common Gaucher Disease Mutant, N370S

Marc N. Offman, Marcin Król, Israel Silman et al. · Journal of Biological Chemistry · 2010 · 34 citations · Full text

Novel use of a genetic algorithm for protein structure prediction: Searching template and sequence alignment space

Bruno Contreras‐Moreira, Paul W. Fitzjohn, Marc N. Offman et al. · Proteins Structure Function and Bioinformatics · 2003 · 30 citations