Changes in ambient temperature differentially alter the thermoregulatory, cardiac and locomotor stimulant effects of 4-methylmethcathinone (mephedrone)

Michelle L. Miller, Kevin M. Creehan, Deepshikha Angrish, +4

Drug and Alcohol Dependence

HyperthermiaMedicinePhysiologyNeuropharmacologyExperimental Pharmacology +4

Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats

Shawn M. Aarde, Deepshikha Angrish, Deborah Barlow, +6

Addiction Biology

Effect of Ambient Temperature on the Thermoregulatory and Locomotor Stimulant Effects of 4-Methylmethcathinone in Wistar and Sprague-Dawley Rats

M. Jerry Wright, Deepshikha Angrish, Shawn M. Aarde, +8

PLoS ONE

The antipsychotic medication, risperidone, causes global immunosuppression in healthy mice

Meghan May, Megan Beauchemin, Calvin Vary, +2

PLoS ONE

Atypical Antipsychotic MedicationsElderly PatientsPsychotropic MedicationImmunologyPsychopharmacology +15

Identification of Clinically Viable Quinolinol Inhibitors of Botulinum Neurotoxin A Light Chain

Dejan Caglič, Michelle C. Krutein, Kristin M. Bompiani, +8

Journal of Medicinal Chemistry

Enzyme PlasticityMolecular PharmacologyPotent ToxinsPharmaceutical ScienceBioorganic Chemistry +10

A novel role for dopamine signaling in the pathogenesis of bone loss from the atypical antipsychotic drug risperidone in female mice

Katherine J. Motyl, Megan Beauchemin, Deborah Barlow, +7

Bone

Bone DiseaseBone LossPsychiatryMedicineDopamine Signaling +8

Propranolol Attenuates Risperidone-Induced Trabecular Bone Loss in Female Mice

Katherine J. Motyl, Victoria DeMambro, Deborah Barlow, +5

Endocrinology

Antipsychotic-induced immune dysfunction: A consideration for COVID-19 risk

Meghan May, Matthew Slitzky, Bahman Rostama, +2

Brain Behavior & Immunity - Health

Psychotropic MedicationImmunologyPsychopharmacologyPharmacotherapyAdaptive Immune Challenge +16

Exploring mechanisms of increased cardiovascular disease risk with antipsychotic medications: Risperidone alters the cardiac proteomic signature in mice

Megan Beauchemin, Ramaz Geguchadze, Anyonya R. Guntur, +8

Pharmacological Research

HypertensionCardiovascular DiseasePsychiatryMedicineCardiac Proteomic Signature +8

Synthesis and Structure–Activity Relationships of 5′-Aryl-14-alkoxypyridomorphinans: Identification of a μ Opioid Receptor Agonist/δ Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects

Rakesh H. Vekariya, Wei Lei, Abhisek Ray, +10

Journal of Medicinal Chemistry