Cláudia Bessa

Discovery of a small-molecule protein kinase Cδ-selective activator with promising application in colon cancer therapy

Cláudia Bessa, Joana Soares, Liliana Raimundo et al. · Cell Death and Disease · 2018 · 123 citations · Full text

Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule

Joana Soares, Liliana Raimundo, Nuno A. L. Pereira et al. · Oncotarget · 2015 · 46 citations · Full text

Oxazoloisoindolinones with in vitro antitumor activity selectively activate a p53-pathway through potential inhibition of the p53–MDM2 interaction

Joana Soares, Nuno A. L. Pereira, Ângelo Monteiro et al. · European Journal of Pharmaceutical Sciences · 2014 · 41 citations

Molecular Pharmacology, Medicinal Chemistry, Oncology +12

Enhanced cytotoxicity of prenylated chalcone against tumour cells via disruption of the p53–MDM2 interaction

Joana Soares, Sara Gomes, Liliana Raimundo et al. · Life Sciences · 2015 · 29 citations

Chemoprevention Strategy, P53–mdm2 Interaction, Medicine +10

Novel simplified yeast-based assays of regulators of p53-MDMX interaction and p53 transcriptional activity

Sara Gomes, Joana Soares, Cláudia Bessa et al. · FEBS Journal · 2013 · 16 citations · Full text

Molecular Regulation, Molecular Biology, Yeast-based Assays +19