Joana Soares

Discovery of a small-molecule protein kinase Cδ-selective activator with promising application in colon cancer therapy

Cláudia Bessa, Joana Soares, Liliana Raimundo et al. · Cell Death and Disease · 2018 · 123 citations · Full text

Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule

Joana Soares, Liliana Raimundo, Nuno A. L. Pereira et al. · Oncotarget · 2015 · 46 citations · Full text

DIMP53-1: a novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer properties

Joana Soares, Margarida Espadinha, Liliana Raimundo et al. · Molecular Oncology · 2017 · 44 citations · Full text

Tumor Biology, Medicinal Chemistry, Transcription Factor P53 +15

Oxazoloisoindolinones with in vitro antitumor activity selectively activate a p53-pathway through potential inhibition of the p53–MDM2 interaction

Joana Soares, Nuno A. L. Pereira, Ângelo Monteiro et al. · European Journal of Pharmaceutical Sciences · 2014 · 41 citations

Molecular Pharmacology, Medicinal Chemistry, Oncology +12

A tryptophanol-derived oxazolopiperidone lactam is cytotoxic against tumors via inhibition of p53 interaction with murine double minute proteins

Joana Soares, Liliana Raimundo, Nuno A. L. Pereira et al. · Pharmacological Research · 2015 · 41 citations · Full text

Tumor Biology, P53 Interaction, Medicine +8