Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection

David Adlam, Timothy M. Olson, Nicolas Combaret, +17

Journal of the American College of Cardiology

Vascular DiseaseCardiovascular DiseaseGeneticsGenetic EpidemiologyPhactr1/edn1 Genetic Locus +9

Kinesin's cover-neck bundle folds forward to generate force

Ahmad S. Khalil, David Appleyard, Anna Labno, +5

Proceedings of the National Academy of Sciences

EngineeringGeometryMolecular BiologyCytoskeletonMechanotransduction +18

The transcription factor FOXL2 mobilizes estrogen signaling to maintain the identity of ovarian granulosa cells

Adrien Georges, David L’Hôte, Anne‐Laure Todeschini, +4

eLife

GynecologyFemale Reproductive SystemFemale Reproductive FunctionReproductive BiologyOvarian Aging +19

Transcription factor FOXL2 protects granulosa cells from stress and delays cell cycle: role of its regulation by the SIRT1 deacetylase

Bérénice A. Benayoun, Adrien Georges, David L’Hôte, +7

Human Molecular Genetics

GeneticsCell CycleCellular PhysiologyTumor BiologyOxidative Stress +18

Functional Exploration of the Adult Ovarian Granulosa Cell Tumor-Associated Somatic FOXL2 Mutation p.Cys134Trp (c.402C>G)

Bérénice A. Benayoun, Sandrine Caburet, Aurélie Dipietromaria, +9

PLoS ONE

FOXL2, GATA4, and SMAD3 Co-Operatively Modulate Gene Expression, Cell Viability and Apoptosis in Ovarian Granulosa Cell Tumor Cells

Mikko Anttonen, Marjut Pihlajoki, Noora Andersson, +7

PLoS ONE

Gct PathogenesisGct Cell ApoptosisApoptosisCell DeathNormal Human Ovary +14

Discovery of novel protein partners of the transcription factor FOXL2 provides insights into its physiopathological roles

David L’Hôte, Adrien Georges, Anne‐Laure Todeschini, +4

Human Molecular Genetics

Genome-Wide Association Study–Driven Gene-Set Analyses, Genetic, and Functional Follow-Up Suggest <i>GLIS1</i> as a Susceptibility Gene for Mitral Valve Prolapse

Mengyao Yu, Adrien Georges, Nathan R. Tucker, +14

Circulation Genomic and Precision Medicine

A plasma proteogenomic signature for fibromuscular dysplasia

Jeffrey W. Olin, Antonio Di Narzo, Valentina d’Escamard, +21

Cardiovascular Research

Rare loss-of-function mutations of <i>PTGIR</i> are enriched in fibromuscular dysplasia

Adrien Georges, Juliette Albuisson, Takiy-Eddine Berrandou, +33

Cardiovascular Research