John K. Thuita

Diamidines for human African trypanosomiasis.

Mary F. Paine, Michael Zhuo Wang, Claudia Generaux et al. · PubMed · 2010 · 117 citations

Medicinal Chemistry, Human African Trypanosomiasis, Pharmaceutical Science +13

Efficacy of the diamidine DB75 and its prodrug DB289, against murine models of human African trypanosomiasis

John K. Thuita, Simon Karanja, Tanja Wenzler et al. · Acta Tropica · 2008 · 90 citations

Translational Medicine, Antiparasitic Agent, Medicine +10

Trypanosoma brucei rhodesiense Transmitted by a Single Tsetse Fly Bite in Vervet Monkeys as a Model of Human African Trypanosomiasis

John K. Thuita, John Kagira, David Mumo Mwangangi et al. · PLoS neglected tropical diseases · 2008 · 53 citations · Full text

Biology, Parasitic Disease, Human African Trypanosomiasis +13

Pharmacology of DB844, an Orally Active aza Analogue of Pafuramidine, in a Monkey Model of Second Stage Human African Trypanosomiasis

John K. Thuita, Michael Z. Wang, John Kagira et al. · PLoS neglected tropical diseases · 2012 · 39 citations · Full text

Efficacy of the Novel Diamidine Compound 2,5-Bis(4-Amidinophenyl)- Furan-Bis- <i>O</i> -Methlylamidoxime (Pafuramidine, DB289) against <i>Trypanosoma brucei rhodesiense</i> Infection in Vervet Monkeys after Oral Administration

Raymond E. Mdachi, John K. Thuita, John Kagira et al. · Antimicrobial Agents and Chemotherapy · 2008 · 38 citations · Full text

Parasitic Disease, Antiparasitic Agent, Malaria +20