Hepatic stellate cell autophagy inhibits extracellular vesicle release to attenuate liver fibrosis

Jinhang Gao, Bo Wei, Thiago M. de Assuncao, +7

Journal of Hepatology

Liver FibrosisPathologyFatty Liver DiseaseCholangiopathiesCirrhosis +15

Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension

Moira Hilscher, Tejasav S. Sehrawat, Juan Pablo Arab, +14

Gastroenterology

EngineeringMechanotransductionCellular PhysiologyInflammationBiomechanics +16

STING mediates hepatocyte pyroptosis in liver fibrosis by Epigenetically activating the NLRP3 inflammasome

Yang Xiao, Chong Zhao, Yang Tai, +9

Redox Biology

Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis

Mengfei Liu, Sheng Cao, Li He, +19

Nature Communications

Endothelial p300 Promotes Portal Hypertension and Hepatic Fibrosis Through C‐C Motif Chemokine Ligand 2–Mediated Angiocrine Signaling

Jinhang Gao, Bo Wei, Mengfei Liu, +11

Hepatology

Mechanotransduction-induced glycolysis epigenetically regulates a CXCL1-dominant angiocrine signaling program in liver sinusoidal endothelial cells in vitro and in vivo

Thomas Greuter, Usman Yaqoob, Can Gan, +15

Journal of Hepatology

MechanobiologySignal TransductionAngiogenesisEndothelial CellsCxcl1-dominant Angiocrine +12

De-methylation of displacement loop of mitochondrial DNA is associated with increased mitochondrial copy number and nicotinamide adenine dinucleotide subunit 2 expression in colorectal cancer

Jinhang Gao, Shilei Wen, Hongying Zhou, +1

Molecular Medicine Reports

Epigenetic ChangeGeneticsDna MethylationMolecular BiologyPathology +21

Precise prediction of phase-separation key residues by machine learning

Jun Sun, Jiale Qu, Cai Zhao, +21

Nature Communications

Low NLRP3 expression predicts a better prognosis of colorectal cancer

Feng Shi, Bo Wei, Tian Lan, +5

Bioscience Reports

Celecoxib Ameliorates Portal Hypertension of the Cirrhotic Rats through the Dual Inhibitory Effects on the Intrahepatic Fibrosis and Angiogenesis

Jinhang Gao, Shilei Wen, Wenjuan Yang, +5

PLoS ONE