Gildas Bertho

Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/β-TrCP Axis

Patricia Rada, Ana I. Rojo, Nathalie Evrard‐Todeschi et al. · Molecular and Cellular Biology · 2012 · 469 citations · Full text

Cytochromes P450 Catalyze Both Steps of the Major Pathway of Clopidogrel Bioactivation, whereas Paraoxonase Catalyzes the Formation of a Minor Thiol Metabolite Isomer

Patrick M. Dansette, Julien Rosi, Gildas Bertho et al. · Chemical Research in Toxicology · 2011 · 115 citations

Thiol Metabolite Isomers, Major Pathway, Lipid Peroxidation +17

Metabolic Oxidative Cleavage of Thioesters: Evidence for the Formation of Sulfenic Acid Intermediates in the Bioactivation of the Antithrombotic Prodrugs Ticlopidine and Clopidogrel

Patrick M. Dansette, Julie Libraire, Gildas Bertho et al. · Chemical Research in Toxicology · 2009 · 95 citations

Lipid Peroxidation, Metabolomic Profiling, Secondary Metabolite +17

First evidence that cytochrome P450 may catalyze both S-oxidation and epoxidation of thiophene derivatives

Patrick M. Dansette, Gildas Bertho, Daniel Mansuy · Biochemical and Biophysical Research Communications · 2005 · 88 citations

Biochemistry, First Evidence, Natural Sciences +7

The First Water-Soluble Copper(I) Calix[6]arene Complex Presenting a Hydrophobic Ligand Binding Pocket: A Remarkable Model for Active Sites in Metalloenzymes

Yannick Rondelez, Gildas Bertho, Olivia Reinaud · Angewandte Chemie International Edition · 2002 · 75 citations

Engineering, Active Sites, Molecular Biology +16