Patrick M. Dansette

Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug.

Philippe Beaune, Patrick M. Dansette, Daniel Mansuy et al. · Proceedings of the National Academy of Sciences · 1987 · 324 citations · Full text

Life Sciences, Biochemistry, Immunology +17

Effects of Inducers and Epoxide Hydrase on the Metabolism of Benzo[ <i>a</i> ]pyrene by Liver Microsomes and a Reconstituted System: Analysis by High Pressure Liquid Chromatography

Gerald M. Holder, Haruhiko Yagi, Patrick M. Dansette et al. · Proceedings of the National Academy of Sciences · 1974 · 210 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Ferrocenyl Quinone Methides as Strong Antiproliferative Agents: Formation by Metabolic and Chemical Oxidation of Ferrocenyl Phenols

Didier Hamels, Patrick M. Dansette, Elizabeth A. Hillard et al. · Angewandte Chemie International Edition · 2009 · 189 citations

Life Sciences, Biochemistry, Chemistry +15

Structure of a Substrate Complex of Mammalian Cytochrome P450 2C5 at 2.3 Å Resolution:  Evidence for Multiple Substrate Binding Modes^,

Michael R. Wester, Eric F. Johnson, Cristina Marques‐Soares et al. · Biochemistry · 2003 · 181 citations

Life Sciences, Biochemistry, Biology +16

Thiophene derivatives as new mechanism-based inhibitors of cytochromes P-450: Inactivation of yeast-expressed human liver cytochrome P-450 2C9 by tienilic acid

M. Pilar López-García, Patrick M. Dansette, Daniel Mansuy · Biochemistry · 1994 · 171 citations

Medicine, Biochemistry, Pharmacology +14