Cristina Marques‐Soares

Structure of a Substrate Complex of Mammalian Cytochrome P450 2C5 at 2.3 Å Resolution:  Evidence for Multiple Substrate Binding Modes^,

Michael R. Wester, Eric F. Johnson, Cristina Marques‐Soares et al. · Biochemistry · 2003 · 181 citations

Structure of Mammalian Cytochrome P450 2C5 Complexed with Diclofenac at 2.1 Å Resolution:  Evidence for an Induced Fit Model of Substrate Binding^,

Michael R. Wester, Eric F. Johnson, Cristina Marques‐Soares et al. · Biochemistry · 2003 · 168 citations

Induced Fit Model, Drug Target, Molecular Biology +18

Substrate selectivity of human cytochrome P450 2C9: importance of residues 476, 365, and 114 in recognition of diclofenac and sulfaphenazole and in mechanism-based inactivation by tienilic acid

Armelle Melet, Nadine Assrir, Pascale Jean et al. · Archives of Biochemistry and Biophysics · 2002 · 99 citations

Substrate Selectivity, Tienilic Acid, Medicinal Chemistry +10

Analysis of Human Cytochrome P450 2C8 Substrate Specificity Using a Substrate Pharmacophore and Site-Directed Mutants

Armelle Melet, Cristina Marques‐Soares, G. Schoch et al. · Biochemistry · 2004 · 49 citations

Retinoic Acid, Molecular Biology, Substrate Pharmacophore +16

Synthesis of Sulfaphenazole Derivatives and Their Use as Inhibitors and Tools for Comparing the Active Sites of Human Liver Cytochromes P450 of the 2C Subfamily

Nguyêt‐Thanh Ha‐Duong, Sylvie Dijols, Cristina Marques‐Soares et al. · Journal of Medicinal Chemistry · 2001 · 30 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Active Sites +18