Placental mTOR complex 1 regulates fetal programming of obesity and insulin resistance in mice

Brian Akhaphong, Daniel Baumann, Megan Beetch, +9

JCI Insight

Metabolic DisorderGeneticsInsulin SignalingObesityMetabolic Syndrome +22

Stilbenoid‐Mediated Epigenetic Activation of Semaphorin 3A in Breast Cancer Cells Involves Changes in Dynamic Interactions of DNA with DNMT3A and NF1C Transcription Factor

Megan Beetch, Katarzyna Lubecka, Kate Shen, +5

Molecular Nutrition & Food Research

Pterostilbene leads to DNMT3B-mediated DNA methylation and silencing of OCT1-targeted oncogenes in breast cancer cells

Megan Beetch, Cayla Boycott, Sadaf Harandi‐Zadeh, +12

The Journal of Nutritional Biochemistry

ChromatinDnmt3b-mediated Dna MethylationOncogenic AgentMedicineEpigenetic Change +8

DNA methylation landscape of triple-negative ductal carcinoma in situ (DCIS) progressing to the invasive stage in canine breast cancer

Megan Beetch, Sadaf Harandi‐Zadeh, T.Y. Yang, +4

Scientific Reports

Disruption of O-Linked N-Acetylglucosamine Signaling in Placenta Induces Insulin Sensitivity in Female Offspring

Mackenzie Moore, Nandini Avula, Seokwon Jo, +2

International Journal of Molecular Sciences

Sex Differences in Pancreatic β-Cell Physiology and Glucose Homeostasis in C57BL/6J Mice

Seokwon Jo, Megan Beetch, Eric Gustafson, +7

Journal of the Endocrine Society

Loci-specific differences in blood DNA methylation in HBV-negative populations at risk for hepatocellular carcinoma development

Katarzyna Lubecka, Kirsty Flower, Megan Beetch, +11

Epigenetics

Epigenetic ChangeGeneticsDna MethylationPathologyEpigenetics +19

O-linked N-acetylglucosamine transferase (OGT) regulates pancreatic α-cell function in mice

Ahmad Essawy, Seokwon Jo, Megan Beetch, +3

Journal of Biological Chemistry

Pterostilbene Changes Epigenetic Marks at Enhancer Regions of Oncogenes in Breast Cancer Cells

Sadaf Harandi‐Zadeh, Cayla Boycott, Megan Beetch, +9

Antioxidants

Subtle Alterations in DNA Methylation Patterns in Normal Cells in Response to Dietary Stilbenoids

Megan Beetch, Katarzyna Lubecka, Heather Kristofzski, +2

Molecular Nutrition & Food Research