Raffaella Pacchiana

Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O2ˉ· production in cancer cells

Marco Cordani, Giovanna Butera, Ilaria Dando et al. · British Journal of Cancer · 2018 · 85 citations · Full text

Do Astrocytes Collaborate with Neurons in Spreading the “Infectious” Aβ and Tau Drivers of Alzheimer’s Disease?

Ilaria Dal Prà, Anna Chiarini, Li Gui et al. · The Neuroscientist · 2014 · 70 citations

Tau Oligomers, Sporadic Alzheimer, Neurochemical Biomarkers +26

The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition

Jessica Brandi, Daniela Cecconi, Marco Cordani et al. · Free Radical Biology and Medicine · 2016 · 68 citations · Full text

Pancreatic Cancer, Pkm2 Expression, Biochemistry +7

Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25–35 in human cortical astrocytes and neurons—Therapeutic relevance to Alzheimer's disease

Ubaldo Armato, Anna Chiarini, Balu Chakravarthy et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2013 · 65 citations

Synaptic Transmission, Synaptic Signaling, Nps 2143 +19

UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism

Ilaria Dando, Raffaella Pacchiana, Elisa Dalla Pozza et al. · Free Radical Biology and Medicine · 2017 · 62 citations

Signal Transduction, Signaling Pathway, G Protein-coupled Receptor +9