3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope–specific plasma cells and humoral immunity in nonhuman primates

Sudhir Pai Kasturi, Mohammed Ata Ur Rasheed, Colin Havenar‐Daughton, +27

Science Immunology

ImmunologyImmunodominanceImmunotherapeuticsNonhuman PrimatesImmunotherapy +19

B Cell Responses during Secondary Dengue Virus Infection Are Dominated by Highly Cross-Reactive, Memory-Derived Plasmablasts

Lalita Priyamvada, Alice Cho, Nattawat Onlamoon, +9

Journal of Virology

Nitric oxide reduces NADPH oxidase 5 (Nox5) activity by reversible S-nitrosylation

Jin Qian, Feng Chen, Yevgeniy Kovalenkov, +7

Free Radical Biology and Medicine

BiochemistryReactive Nitrogen SpecieReversible S-nitrosylationReactive Oxygen SpecieMedicine +4

Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques

Sudhir Pai Kasturi, Pamela A. Kozlowski, Helder I. Nakaya, +22

Journal of Virology

Molecular mechanisms mediating protective effect of cAMP on lipopolysaccharide (LPS)‐induced human lung microvascular endothelial cells (HLMVEC) hyperpermeability

Natalia V. Bogatcheva, Marina A. Zemskova, Yevgeniy Kovalenkov, +2

Journal of Cellular Physiology

Protein SecretionLung InflammationImmunologyBarrier CompromisePka Activation +17

Vaccine induction of antibodies and tissue-resident CD8+ T cells enhances protection against mucosal SHIV-infection in young macaques

Caroline Petitdemange, Sudhir Pai Kasturi, Pamela A. Kozlowski, +23

JCI Insight

Robust memory responses against influenza vaccination in pemphigus patients previously treated with rituximab

Alice Cho, Bridget Bradley, Robert C. Kauffman, +4

JCI Insight

Humoral ResponseImmunologyImmunodominanceRobust Memory ResponsesFlu Vaccination +17

Vaccine-induced plasmablast responses in rhesus macaques: Phenotypic characterization and a source for generating antigen-specific monoclonal antibodies

Eduardo L. V. Silveira, Sudhir Pai Kasturi, Yevgeniy Kovalenkov, +7

Journal of Immunological Methods

VaccinationVaccine DevelopmentAntigen-specific Monoclonal AntibodiesRhesus MacaquesVaccine Target +7

Circadian Clock Control of Nox4 and Reactive Oxygen Species in the Vasculature

Ciprian B. Anea, Maoxiang Zhang, Feng Chen, +8

PLoS ONE

Circadian ClockReactive Oxygen SpeciesRedox BiologyOxidative StressInflammation +17

Novel Mechanism of Attenuation of LPS-Induced NF-κB Activation by the Heat Shock Protein 90 Inhibitor, 17-N-allylamino-17-demethoxygeldanamycin, in Human Lung Microvascular Endothelial Cells

Gagan Thangjam, C. Dimitropoulou, Atul Joshi, +7

American Journal of Respiratory Cell and Molecular Biology

Inflammatory Lung DiseaseLung InflammationImmunologyImmune RegulationInflammation +17