Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically characterised cohort☆

Quentin M. Anstee, Rebecca Darlay, Simon Cockell, +26

Journal of Hepatology

Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis

Olivier Govaere, Simon Cockell, Dina Tiniakos, +26

Science Translational Medicine

Contribution of Global Rare Copy-Number Variants to the Risk of Sporadic Congenital Heart Disease

Rachel Soemedi, Ian Wilson, Jamie Bentham, +28

The American Journal of Human Genetics

A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation

Marijana Vujković, Shweta Ramdas, Kimberly Lorenz, +84

Nature Genetics

Genome-wide Association StudyMetabolic SyndromeMetabolic Associated SteatohepatitisHepatologyMetabolic Associated Steatotic Liver Disease +13

Phenotype-specific effect of chromosome 1q21.1 rearrangements and GJA5 duplications in 2436 congenital heart disease patients and 6760 controls

Rachel Soemedi, Ana Töpf, Ian Wilson, +25

Human Molecular Genetics

Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease

Olivier Govaere, Sine Kragh Petersen, Nuria Martínez-López, +36

Journal of Hepatology

InflammationMetabolic SyndromeMetabolic Associated SteatohepatitisHepatologyNonalcoholic Fatty Liver Disease +13

The influence of HLA genotype on the severity of COVID‐19 infection

David Langton, Stephen C Bourke, Benedicte A. Lie, +5

HLA

Virus EpidemiologyCovid‐19 InfectionImmunologyGenetic EpidemiologyCovid-19 Epidemiology +16

Genome-wide association study identifies loci on 12q24 and 13q32 associated with Tetralogy of Fallot

Heather J. Cordell, Ana Töpf, Chrysovalanto Mamasoula, +34

Human Molecular Genetics

A genetic risk score and diabetes predict development of alcohol-related cirrhosis in drinkers

John B. Whitfield, Tae‐Hwi Schwantes‐An, Rebecca Darlay, +38

Journal of Hepatology

Metabolic SyndromeGenetic DeterminantHepatologyMedicineLiver Physiology +12

Whole-Genome Linkage and Association Scan in Primary, Nonsyndromic Vesicoureteric Reflux

Heather J. Cordell, Rebecca Darlay, Pimphen Charoen, +9

Journal of the American Society of Nephrology

EngineeringGeneticsRenal PathologyGenetic EpidemiologyLinkage Analysis +16