Elizabeth Culp

Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling

Elizabeth Culp, Nicholas Waglechner, Wenliang Wang et al. · Nature · 2020 · 286 citations

Peptoid, Evolution-guided Discovery, Rational Drug Design +5

Hidden antibiotics in actinomycetes can be identified by inactivation of gene clusters for common antibiotics

Elizabeth Culp, Grace Yim, Nicholas Waglechner et al. · Nature Biotechnology · 2019 · 91 citations

Common Antibiotics, Antimicrobial Resistance Gene, Health Sciences +11

Transformation of the Anticancer Drug Doxorubicin in the Human Gut Microbiome

Austin Yan, Elizabeth Culp, Julie Perry et al. · ACS Infectious Diseases · 2017 · 90 citations

Antineoplastic Drug Doxorubicin, Dysbiosis, Antibiotic Adjuvant +19

Microbial transformation of dietary xenobiotics shapes gut microbiome composition

Elizabeth Culp, Nora T Nelson, Andrew A Verdegaal et al. · Cell · 2024 · 65 citations · Full text

Microbiota Structure, Dysbiosis, Gut Microbiology +7

Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development

Samuel Jacques, Almer M. van der Sloot, Caroline Huard et al. · Genetics · 2020 · 63 citations · Full text