Charlotte M. Fryling

Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptors.

George J. Todaro, Charlotte M. Fryling, Joseph E. De Larco · Proceedings of the National Academy of Sciences · 1980 · 909 citations · Full text

Release Proteins, Human Growth, Medicine +15

Human transforming growth factors induce tyrosine phosphorylation of EGF receptors

Fred H. Reynolds, George J. Todaro, Charlotte M. Fryling et al. · Nature · 1981 · 240 citations

Developmental Biology, Signal Transduction, Growth Hormone +8

Cell-mediated cleavage of Pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol.

M Ogata, Charlotte M. Fryling, Ira Pastan et al. · Journal of Biological Chemistry · 1992 · 161 citations · Full text

Microbial Toxin, Active Fragment, 5Th Amino Acid +11

Cleavage of pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver.

Marielle F. Chiron, Charlotte M. Fryling, David Fitzgerald · Journal of Biological Chemistry · 1994 · 130 citations · Full text

Microbial Toxin, Cellular Enzymology, Biochemistry +12

Transforming growth factors (TGFs): Properties and possible mechanisms of action

George J. Todaro, Joseph E. De Larco, Charlotte M. Fryling et al. · Journal of Supramolecular Structure and Cellular Biochemistry · 1981 · 92 citations