Irving L.M.H. Aye

Increasing Maternal Body Mass Index Is Associated with Systemic Inflammation in the Mother and the Activation of Distinct Placental Inflammatory Pathways1

Irving L.M.H. Aye, Susanne Lager, Vanessa Ramírez et al. · Biology of Reproduction · 2014 · 258 citations · Full text

Placental P38-mapk, Immunology, Gynecology +26

Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth

Irving L.M.H. Aye, Fredrick J. Rosario, Theresa L. Powell et al. · Proceedings of the National Academy of Sciences · 2015 · 154 citations · Full text

Nutrition, Fetal Health, Rapamycin Complex 1 +30

Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity

Irving L.M.H. Aye, Brendan J. Waddell, Peter J. Mark et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2010 · 97 citations

Placental Abca1, Protect Trophoblasts, Developmental Biology +9

Interleukin-1β inhibits insulin signaling and prevents insulin-stimulated system A amino acid transport in primary human trophoblasts

Irving L.M.H. Aye, Thomas Jansson, Theresa L. Powell · Molecular and Cellular Endocrinology · 2013 · 93 citations

Inflammation, Cytokine, Primary Human Trophoblasts +12

Placental polyamine metabolism differs by fetal sex, fetal growth restriction, and preeclampsia

Sungsam Gong, Ulla Sovio, Irving L.M.H. Aye et al. · JCI Insight · 2018 · 79 citations · Full text

Fertility, Genetics, Fetal Medicine +24