Mythily Vimal

Discovery of 3-Aryl-4-isoxazolecarboxamides as TGR5 Receptor Agonists

Karen A. Evans, Brian Budzik, Sean Ross et al. · Journal of Medicinal Chemistry · 2009 · 75 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Discovery of a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose through Synergistic Use of Encoded Library Technology and Fragment Screening

Christopher R. Wellaway, Dominique Amans, Paul Bamborough et al. · Journal of Medicinal Chemistry · 2020 · 71 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Synthesis and structure–activity relationships of a series of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor

Laura J. Chambers, Alexander J. Stevens, Andrew P. Moses et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 28 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Blockade of human and porcine myocardial 5-HT4 receptors by SB 203186

StephenG. Parker, E. M. Taylor, StevenA. Hamburger et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 1995 · 22 citations

Medicine, Cardiology, Pharmacology +14

Exploring the SAR of the β-Ketoacyl-ACP Synthase Inhibitor GSK3011724A and Optimization around a Genotoxic Metabolite

Fraser Cunningham, Jorge Esquivias, Raquel Fernández Menéndez et al. · ACS Infectious Diseases · 2020 · 21 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13