Michelle S. Ong

Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation

Scott B. Rothbart, Bradley M. Dickson, Michelle S. Ong et al. · Genes & Development · 2013 · 182 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

A Ruthenium Antimetastasis Agent Forms Specific Histone Protein Adducts in the Nucleosome Core

Bin Wu, Michelle S. Ong, Michael Groessl et al. · Chemistry - A European Journal · 2011 · 173 citations · Full text

Life Sciences, Oncology, Pharmacology +10

DNA Stretching and Extreme Kinking in the Nucleosome Core

Michelle S. Ong, Timothy J. Richmond, Curt A. Davey · Journal of Molecular Biology · 2007 · 143 citations

Life Sciences, Biophysics, Molecular Biology +15

Accessibility of Different Histone H3-Binding Domains of UHRF1 Is Allosterically Regulated by Phosphatidylinositol 5-Phosphate

Kathy A. Gelato, Maria Tauber, Michelle S. Ong et al. · Molecular Cell · 2014 · 129 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Conformational dynamics of the TTD–PHD histone reader module of the UHRF1 epigenetic regulator reveals multiple histone-binding states, allosteric regulation, and druggability

R. Scott Houliston, Alexander Lemak, Aman Iqbal et al. · Journal of Biological Chemistry · 2017 · 46 citations · Full text

Life Sciences, Genetics, Molecular Biology +14