Michał Pawlak

In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice

Kristen Browder, Pradeep Reddy, Mako Yamamoto et al. · Nature Aging · 2022 · 217 citations

Developmental Biology, Aging, Longevity +8

The transrepressive activity of peroxisome proliferator-activated receptor alpha is necessary and sufficient to prevent liver fibrosis in mice

Michał Pawlak, Eric Baugé, William Bourguet et al. · Hepatology · 2014 · 136 citations

Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontin

Philippe Lefèbvre, Fanny Lalloyer, Eric Baugé et al. · JCI Insight · 2017 · 117 citations · Full text

Genetics, Immune Regulation, Immunology +30

Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα

Dariusz Ratman, Viacheslav Mylka, Nadia Bougarne et al. · Nucleic Acids Research · 2016 · 77 citations · Full text

Liver Ampk, Molecular Regulation, Genetics +25

Age-related changes in polycomb gene regulation disrupt lineage fidelity in intestinal stem cells

Helen M. Tauc, Imilce A. Rodriguez‐Fernandez, Jason A. Hackney et al. · eLife · 2021 · 45 citations · Full text