Jacques Y. Roberge

EGT1442, a potent and selective SGLT2 inhibitor, attenuates blood glucose and HbA1c levels in db/db mice and prolongs the survival of stroke-prone rats

Wenbin Zhang, Ajith Welihinda, Jordan Mechanic et al. · Pharmacological Research · 2011 · 76 citations

Selective Sglt2 Inhibitor, Medicine, Diabetes +13

A Strategy for a Convergent Synthesis of N-Linked Glycopeptides on a Solid Support

Jacques Y. Roberge, Xenia Beebe, Samuel J. Danishefsky · Science · 1995 · 76 citations

Combinatorial Chemistry, Bioorganic Chemistry, Peptide Engineering +16

Convergent Synthesis of <i>N</i>-Linked Glycopeptides on a Solid Support

Jacques Y. Roberge, Xenia Beebe, Samuel J. Danishefsky · Journal of the American Chemical Society · 1998 · 70 citations

Biochemistry, Glycal Assembly Method, Natural Sciences +13

Design, Synthesis, and Biological Evaluation of Deuterated <i>C</i>-Aryl Glycoside as a Potent and Long-Acting Renal Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes

Ge Xu, Binhua Lv, Jacques Y. Roberge et al. · Journal of Medicinal Chemistry · 2014 · 63 citations · Full text

Urinary Glucose Excretion, Oxidative Stress, Molecular Pharmacology +16

Discovery of 2-(Phenoxypyridine)-3-phenylureas as Small Molecule P2Y₁ Antagonists

Hannguang J. Chao, Huji Turdi, Timothy F. Herpin et al. · Journal of Medicinal Chemistry · 2013 · 58 citations · Full text

Adp-mediated Platelet Aggregation, Pharmacotherapy, Chemical Biology +20