Telomere length as a prognostic parameter in chronic lymphocytic leukemia with special reference to VH gene mutation status

Pawel Grabowski, Magnus Hultdin, Karin Karlsson, +7

Blood

In vitro evaluation of clinical activity and toxicity of anticancer drugs using tumor cells from patients and cells representing normal tissues

Caroline Haglund, Anna Åleskog, Peter Nygren, +5

Cancer Chemotherapy and Pharmacology

Normal TissuesOncologyMedicineClinical ActivityTumor Cells +8

Patients with chronic lymphocytic leukemia with mutated VH genes presenting with Binet stage B or C form a subgroup with a poor outcome.

Gerard Tobin, Ulf Thunberg, Anna Laurell, +10

PubMed

The G(-248)A polymorphism in the promoter region of the Bax gene does not correlate with prognostic markers or overall survival in chronic lymphocytic leukemia

Å Skogsberg, Gerard Tobin, Alexander Kröber, +14

Leukemia

Hematological MalignancyOncologyPromoter RegionMedicineGenetics +8

Significant cytotoxic activity <i>in vitro</i> of the EGFR tyrosine kinase inhibitor gefitinib in acute myeloblastic leukaemia

Elin Lindhagen, Anna Eriksson, Malin Wickström, +7

European Journal Of Haematology

The FMCA-GM assays, high throughput non-clonogenic alternatives to CFU-GM in preclinical hematotoxicity testing

Caroline Haglund, Anna Åleskog, Lena Håkansson, +4

Toxicology Letters

MedicineBioanalysisHematologyPreclinical HematotoxicityPathology +6

The novel NF-κB inhibitor IMD-0354 induces apoptosis in chronic lymphocytic leukemia

Meena Kanduri, Gerard Tobin, Anna Åleskog, +2

Blood Cancer Journal

Chronic Lymphocytic LeukemiaApoptosisImmunologyCell DeathCancer Biology +15

Activity of CHS 828 in primary cultures of human hematological and solid tumors in vitro

Anna Åleskog, Saadia Bashir-Hassan, Peter Hovstadius, +6

Anti-Cancer Drugs

Solid TumorsPathologyMetronomic ChemotherapyTumor BiologyAcute Leukemia +15

Rapamycin shows anticancer activity in primary chronic lymphocytic leukemia cells<i>in vitro</i>, as single agent and in drug combination

Anna Åleskog, Maria Norberg, Peter Nygren, +7

Leukemia & lymphoma/Leukemia and lymphoma

Cll SamplesImmunologyImmunotherapyTumor BiologyHematological Malignancy +14

Single-tube nested quantitative PCR: a rational and sensitive technique for detection of retroviral DNA. Application to RERV-H/HRV-5 and confirmation of its rabbit origin

Anna Forsman, Dmitrijs Užameckis, Lars Rönnblom, +8

Journal of Virological Methods

Polymerase Chain ReactionDiagnostic VirologyMolecular VirologyRabbit OriginViral Diagnostics +10